Severe malaria not responsive to artemisinin derivatives in man returning from Angola to Vietnam.

01 Jul 2014
Van Hong N, Amambua-Ngwa A, Tuan NQ, Cuong do D, Giang NT, Van Dung N, Tinh TT, Van Tien N, Phuc BQ, Duong TT, Rosanas-Urgell A, D'Alessandro U, Van Geertruyden JP, Erhart A

 

Resistance to artemisinin derivatives, the most potent antimalarial drugs currently used, has emerged in Southeast Asia and threatens to spread to Africa. We report a case of malaria in a man who returned to Vietnam after 3 years in Angola that did not respond to intravenous artesunate and clindamycin or an oral artemisinin-based combination.