Severe Malaria Observatory

Knowledge sharing for severe malaria

  • Search

Search

Search
  • Severe malaria
    • What is malaria?
    • Global burden
    • Symptoms
    • Diagnosis
    • Treatment
    • Groups at risk
  • Countries
    • Angola
    • Burkina Faso
    • Cameroon
    • Central African Republic
    • Ghana
    • Malawi
    • Nigeria
    • Tanzania
    • Uganda
    • Zambia
    • Democratic Republic of Congo
  • Drugs & markets
  • In the field
    • Stories and films
    • Interviews
  • Toolkits & training
    • Injectable artesunate
    • Artesunate Rectal Capsules
    • Additional resources
  • Resources
    • News & Events
      • Events
    • Newsletter
  • About us
    • FAQ

Search

Photo: Toby Madden / MMV

Featured past event: ASTMH Symposium - Severe Malaria: improving the continuum of care

Find out more

Photo: Toby Madden / MMV
Photo: MMV

The Severe Malaria Observatory: Experience. Evidence. Guidance. 

Find out more

Photo: MMV
Photo: Toby Madden/MMV

Click here to see what you missed in our last newsletter. To receive upcoming newsletters, please subscribe. 

Photo: Toby Madden/MMV

Featured resources

Photo: MMV

Watch recorded session on protecting adolescent girls against malaria

01 Mar 2015

Comparaison de l’efficacité de l’artémether et de la quinine dans le traitement du paludisme grave chez les enfants à Bangui, République centrafricaine

Bulletin de la Société de pathologie exotique
Peer-reviewed article
11 Nov 2019

Évaluation de la prise en charge des cas de paludisme grave en RDC

La présente étude a été réalisée pour identifier les obstacles et les opportunités rencontrés dans la prise en charge du paludisme grave afin de réduire la mortalité associée à cette maladie en RDC.  

Severe Malaria Observatory
Severe malaria rapid assessment reports
28 Oct 2011

Injectable artesunate field testing report

Wellsense
Severe malaria rapid assessment reports
25 Mar 2021

Evaluation of the Management of Severe Malaria in Pregnant Women, Children and Adults in Mali

Severe Malaria Observatory
Severe malaria rapid assessment reports
1

Events

22
Apr
2021

Celebrating African Women in the Malaria Response Conference

https://eur02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fus02web.zoom.us%2Fwebinar%2Fregister%2FWN_RjXWxKamTA6rXn0mKp38tQ&data=04%7C01%7Cpoku-awukua%40mmv.org%7C3a1854fcc9d14a3beb2508d900187bd8%7Ce8b17900d5744ad3b2ad88022d70c929%7C1%7C0%7C6375409
1

Latest news

Photo: Transaid

Transaid’s highly successful MAMaZ Against Malaria project is to expand to cover 10 districts in rural Zambia

08 Dec 2020
Photo: Toby Madden / MMV

2020 World Malaria Report highlights the need for a stronger push to increase IPTp coverage of pregnant women

30 Nov 2020
Photo: Anna Wang/MMV

Severe Malaria Observatory launches French website

The Severe Malaria Observatory is pleased to announce the launch of its French website. This website will be a welcome addition which will assist the malaria community and communities impacted by malaria in French speaking countries to access information on severe malaria prevention, treatment as well as national and international policies and guidance. The French website can be found at www.severemalaria.org/fr

19 Nov 2020
Photo: Office of the First Lady of Ghana

International Day of the Girl Child: Get up, speak out and save adolescent girls from malaria

Her Excellency Rebecca Akuffo Addo, First Lady of the Republic of Ghana entreats all African leaders to fully commit to protecting young girls, so they do not die from malaria.

13 Oct 2020
1

Publications

25 Mar 2021

Donor Landscaping Report: Rectal artesunate

Severe Malaria Observatory
Report
25 Mar 2021

Evaluation of the Management of Severe Malaria in Pregnant Women, Children and Adults in Mali

Severe Malaria Observatory
Severe malaria rapid assessment reports
16 Mar 2021

Artesunate rectal capsules verification report

Severe Malaria Observatory
Report
1 Feb 2021

Pharmacokinetic study of rectal artesunate in children with severe malaria in Africa

When severe malaria is suspected in children, WHO recommends pre-treatment with a single rectal dose of artesunate before referral to an appropriate facility. This was an individually randomized, open-label, 2-arm, cross-over clinical trial in 83 Congolese children with severe falciparum malaria, to characterize the pharmacokinetics of rectal artesunate. At admission, children received a single dose of rectal artesunate (10 mg/kg) followed 12 hours later by intravenous artesunate (2.4 mg/kg) or the reverse order. All children also received standard doses of intravenous quinine. Artesunate and dihydroartemisinin were measured at eleven fixed intervals, following 0- and 12-hour drug administrations. Clinical, laboratory and parasitological parameters were measured. 

Antimicrobial agents and Chemotherapy
Peer-reviewed article

Get in touch

Contact us
Submit content

Subscribe

Sign up to our newsletter

Follow us

  • Twitter

Footer menu

  • Disclaimer
  • Privacy Policy
A Remora website by Manta Ray Media