Resources

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Photo: Toby Madden/Transaid
19 Jun 2020

A Rapid Assessment of Severe Malaria Case Management Practices and Constraints in Angola

This study aimed to identify existing gaps in knowledge about severe malaria case management in Angola by collecting information at different health service levels and through different study populations

Medicines for Malaria Initiative
Report
20 Mar 2020

Blood group and size dependent stability of & P. falciparum & infected red blood cell aggregates in capillaries.

For related malaria (B50), one of the outstanding host factors for the development of severe disease is the ABO blood group of malaria patients, where blood group O reduces the probability of severe disease as compared to individuals of groups A, B, or AB.

Biomicrofluidics
Peer-reviewed article
16 Mar 2020

Preparedness is essential for malaria-endemic regions during the COVID-19 pandemic

Africa needs to be prepared to deal with COVID-19, given the infectious potential of the disease and its capacity to undermine malaria control efforts.

The Lancet
12 Mar 2020

Malaria Case Fatality Rate among Children under Five in Burkina Faso: An Assessment of the Spatiotemporal Trends Following the Implementation of Control Programs.

The findings of this research highlighted locations in Burkina Faso that are most in need of targeted interventions and the necessity to sustain and strengthen the launched health programs to further reduce the malaria deaths in Burkina Faso.
11 Mar 2020

Imported Malaria in Countries where Malaria Is Not Endemic: a Comparison of Semi-immune and Nonimmune Travelers.

The continuous increase in long-distance travel and recent large migratory movements have changed the epidemiological characteristics of imported malaria in countries where malaria is not endemic (here termed non-malaria-endemic countries).

Clin Microbiol Rev
Peer-reviewed article
06 Mar 2020

Optimizing iron supplementation for children with severe malaria.

The safe and efficacious provision of iron supplementation in areas of high infectious disease burden is a critical and sometimes controversial global health issue.

Am J Clin Nutr
Peer-reviewed article
03 Mar 2020

Post-artemisinin delayed hemolysis after oral therapy for P. falciparum infection.

A documented side-effect of artemisinin therapy is post-artemisinin delayed hemolysis (PADH), primarily occurring after parenteral treatment for severe P. falciparum infections.

IDCases
Peer-reviewed article
26 Feb 2020

Overexpression of Sphingosine Kinase-1 and Sphingosine-1-Phosphate Receptor-3 in Severe <i>Plasmodium falciparum</i> Malaria with Pulmonary Edema.

Pulmonary edema (PE) is a major cause of pulmonary manifestations of severe malaria and is usually associated with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS).

Biomed Res Int
Peer-reviewed article
24 Feb 2020

Association of EPCR Polymorphism rs867186-GG With Severity of Human Malaria.

Cerebral malaria (CM) is characterized by the sequestration of Plasmodium-infected erythrocytes (pRBCs) to host brain microvasculature beds via P. falciparum erythrocyte membrane protein 1 (PfEMP1)

Front Genet
Peer-reviewed article
01 Feb 2020

HRP2: Transforming Malaria Diagnosis, but with Caveats.

The major growth in point-of-care malaria diagnosis over the past decade has been based on immunochromatographic malaria rapid diagnostic tests (mRDTs)

Trends Parasitol
Peer-reviewed article
15 Jan 2020

Desperately Seeking Therapies for Cerebral Malaria.

Malaria is a deadly infectious disease caused by parasites of the Plasmodium spp. that takes an estimated 435,000 lives each year, primarily among young African children.

J Immunol
Peer-reviewed article
14 Jan 2020

Platelet α-granules contribute to organ-specific pathologies in a mouse model of severe malaria.

In this study, we address the role of platelets in the development of severe malaria in 3 different mouse models of platelet dysfunction/depletion. We show a key role for platelets, particularly platelet α-granules, in mediating organ-specific pathologies during rodent Plasmodium infection.

Blood Adv
Peer-reviewed article

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