Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial

27 Aug 2005
South East Asian Quinine Artesunate Malaria Trial (SEAQUAMAT) group

An open-label randomised controlled trial in patients admitted to hospital with severe falciparum malaria in Bangladesh, India, Indonesia, and Myanmar. Patients were assigned intravenous artesunate or intravenous quinine. The primary endpoint was death from severe malaria, and analysis was by intention to treat.