<i>G6PD</i> and <i>HBB</i> polymorphisms in the Senegalese population: prevalence, correlation with clinical malaria.

Host genetic factors contribute to the variability of malaria phenotypes and can allow a better understanding of mechanisms involved in susceptibility and/or resistance to infection outcomes. Several genetic polymorphisms were reported to be prevalent among populations living in tropical malaria-endemic regions and induce protection against malaria. The present study aims to investigate the prevalence of and deficiencies polymorphisms among Senegalese populations and their associations with the risk for severe malaria occurrence.